
Fas receptor - Wikipedia
The Fas receptor, also known as Fas, FasR, apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6), is a protein that in humans is encoded by the FAS gene.
FAS Gene - GeneCards | TNR6 Protein | TNR6 Antibody
Dec 25, 2024 · FAS (Fas Cell Surface Death Receptor) is a Protein Coding gene. Diseases associated with FAS include Autoimmune Lymphoproliferative Syndrome and Lymphoma. Among its related pathways are CASP8 activity is inhibited and TNFR1 Pathway.
FAS gene: MedlinePlus Genetics
The FAS gene provides instructions for making a protein that is involved in cell signaling. Three FAS proteins group together to form a structure called a trimer, which then interacts with other molecules to perform its signaling function. This signaling initiates a process called a …
The many roles of FAS receptor signaling in the immune system
FAS (also known as APO-1 or CD95) belongs to the subgroup of the tumor necrosis factor receptor (TNF-R) family that contain an intra-cellular ‘death domain’ and can trigger apoptosis. Its physiological ligand, FASL (CD95L), is a member of the corresponding TNF cytokine family.
Fas ligand - Wikipedia
Fas ligand (FASL or CD95L) is a type-II transmembrane protein expressed on various types of cells, including cytotoxic T lymphocytes, monocytes, neutrophils, breast epithelial cells, vascular endothelial cells and natural killer (NK) cells.
The genetic landscape of the FAS pathway deficiencies
Aug 1, 2021 · FAS (TNFRSF6) is the sixth member of the Tumor Necrosis Factor Receptor (TNFR) superfamily (NCBI gene ID:355). It is a membrane-bound trimeric protein playing a key role in apoptosis. The FAS gene, located on the long-arm of the chromosome 10 (10q23.3–4) in human and on the chromosome 19 in mice, is composed of 9 exons encoding a type-I protein.
FAS Fas cell surface death receptor [ Homo sapiens (human) ]
Dec 3, 2024 · Note: FAS (Gene ID: 355) and FASN (Gene ID: 2194) share the FAS symbol/alias in common. FAS is a widely used alternative name for fatty acid synthase (FASN), which can be confused with the official symbol for FAS (Fas cell surface death receptor, GeneID 355).
Entry - *134637 - FAS CELL SURFACE DEATH RECEPTOR; FAS
Yan et al. (2005) described a novel RNA transcribed from the opposite strand of intron 1 of the human FAS gene, which they named SAF. The 1.5-kb transcript was expressed in human heart, placenta, liver, muscle, and pancreas, as well as in several cancer cell lines.
355 - Gene ResultFAS Fas cell surface death receptor [ (human)]
Feb 8, 2025 · Gene ID: 355, updated on 8-Feb-2025. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain.
FAS Fas cell surface death receptor - NIH Genetic Testing …
Dec 3, 2024 · The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.