
Forkhead box protein O1 - Wikipedia
Forkhead box protein O1 (FOXO1), also known as forkhead in rhabdomyosarcoma (FKHR), is a protein that in humans is encoded by the FOXO1 gene. [5] FOXO1 is a transcription factor that …
FOXO1 Gene - GeneCards | FOXO1 Protein | FOXO1 Antibody
Dec 25, 2024 · FOXO1 (Forkhead Box O1) is a Protein Coding gene. Diseases associated with FOXO1 include Rhabdomyosarcoma 2 and Diffuse Large B-Cell Lymphoma. Among its …
FOXO1 is a master regulator of memory programming in CAR T cells
Apr 10, 2024 · Our results show that overexpressing FOXO1 can increase the antitumour activity of human CAR T cells, and highlight memory reprogramming as a broadly applicable approach …
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
Apr 10, 2024 · Here we show that overexpression of FOXO1 promotes a stem-like phenotype in CAR T cells derived from either healthy human donors or patients, which correlates with …
FOXO1: A potential target for human diseases - PMC - PubMed …
Here we give an overview of most recent findings regarding the regulation and function of FoxO1, its potential role in human diseases and useful animal models for functional studies on FoxO1.
The regulation of FOXO1 and its role in disease progression
Jan 15, 2018 · In periodontal mesenchymal stem cells (PDLSCs) from periodontitis patients, lncRNA and miR-182 suppress each other and form a network to regulate FOXO1. FOXO1 …
A Review of FoxO 1-Regulated Metabolic Diseases and Related …
Jan 10, 2020 · FoxO1 is a conserved transcription factor involved in energy metabolism. It is tightly regulated by modifications on its mRNA and protein and responds to environmental …
FOXO1 forkhead box O1 [Homo sapiens (human)] - Gene - NCBI
Nov 8, 2021 · Title: FoxO1-Overexpressed Small Extracellular Vesicles Derived from hPDLSCs Promote Periodontal Tissue Regeneration by Reducing Mitochondrial Dysfunction to Regulate …
FOXO1 forkhead box O1 [ (human)] - National Center for …
FOXO1 regulates wound-healing responses in human gingival fibroblasts. FOXO1 promotes cancer cell growth through MDM2-mediated p53 degradation. An extensive analysis of the …
FOXO transcription factors throughout T cell biology
Aug 24, 2012 · FOXO1 and FOXO3 are the major FOXO paralogues expressed in T cells, and they have distinct (but sometimes overlapping) functions in T cell survival and differentiation. …
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