FTH1 indicates poor prognosis and promotes metastasis in head …
The overexpression of FTH1 in tumor tissues may be a good indicator of its cancer-promoting function. In addition to ferroptosis, upregulation of FTH1 may promote the invasion and …
A comprehensive pan-cancer analysis of prognostic value and
Jan 28, 2024 · Single-cell sequencing analysis and multiplex immunofluorescence staining techniques are applied to observe FTH1 co-expression on both tumor and immune cells. FTH1 …
A comprehensive pan-cancer analysis of prognostic value and …
Analyzing tumor and normal samples from the TCGA dataset revealed significant upregulation of FTH1 in 10 tumors (BRCA, ESCA, KIRP, UCEC, HNSC, KIRC, LIHC, THCA, KICH, CHOL) …
Ferritin heavy chain (FTH1) exerts significant antigrowth effects in ...
Overexpression of ferritin heavy chain (FTH1) often associates with good prognosis in breast cancer (BCa), particularly in the triple‐negative subtype (triple‐negative breast cancer). …
FTH promotes the proliferation and renders the HCC cells …
Dec 29, 2021 · We explored the correlation of FTH1 with infiltrating immune cells (CD8 + T cells, CD4 + T cells, B cells, dendritic cells macrophages, and neutrophils) and tumor purity in HCC …
Predictive value of circulating tumor cells FTH1 gene on the …
Jun 2, 2022 · CTCs with high expression of the FTH1 gene (HEF) may be related to poor efficacy of neoadjuvant chemotherapy (NAC). The relation between the CTCs with HEF and …
A comprehensive pan-cancer analysis of prognostic value and
Jan 28, 2024 · Results: FTH1 exhibited aberrant expression patterns across multiple cancers, which is strongly correlated with immunotherapy resistance. Patients with high FTH1 …
Dual ferroptosis induction in N2-TANs and TNBC cells via FTH1 …
Jan 21, 2025 · By targeting FTH1, CT-1 facilitates the interaction between NCOA4 and ferritin, triggering ferritinophagy-mediated ferroptosis. These findings position CT-1 as a promising …
Frontiers | High expression level of the FTH1 gene is associated …
Jan 31, 2023 · Through survival analysis, FTH1 was identified as a key gene associated with AML prognosis. We verified the proliferative and regulatory effects of ferroptosis on MOLM-13 and …
Association of FTH1-Expressing Circulating Tumor Cells With …
To evaluate the association of ferritin heavy chain (FTH1)-expressing circulating tumor cells (CTCs) with the efficacy of neoadjuvant chemotherapy (NAC) for patients with breast cancer, …