Jan 22, 2023 · Herein we describe a method to produce 2-haloalkoxy-3-substituted quinolines via the cyclization of 2-alkynylanilines with TMSCF 3 and THF.

Dec 12, 2020 · Nav1.8 is primarily restricted to pain sensing neurons, and a results, it has been hypothesized that selective Nav1.8 blockers may be useful for the treatment of pain disorders. …

Feb 3, 2023 · Herein we describe a method to produce 2-haloalkoxy-3-substituted quinolines via the cyclization of 2-alkynylanilines with TMSCF 3 and THF. This synthetic method uses …

Oct 15, 1993 · 2-(Haloalkoxy)pyridines thermally rearrange to N-haloalkyl-2(1H)-pyridones in high yield. The reaction rate is accelerated by use of a more polar solvent, by bromine rather than …

Oct 30, 2001 · The oxaspirocyclopropanation and the one-pot hydroxycyclopropanation of simple alkenes have been accomplished by thermal treatment with 2- and 3-haloalkoxy …

Apr 22, 2015 · A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an S N 2-type ring opening followed by …

The invention relates to a method for synthesizing 1- (haloalkoxy) -2-alkoxy-5-nitrobenzene compounds, which comprises the following steps: adding 2-alkoxy-5-nitrophenol or salt …

Quinoline synthesis: scope and regiochemistry of photocyclisation of substituted benzylidenecyclopentanone O-alkyl and O-acetyloximes.

In the case of the dimethylamino derivative it was established that thermolysis gives a mixture of oxooxazolo- and oxoimidazo-sym-triazines, the structures of which were proved by data from …

Feb 3, 2023 · Herein we describe a method to produce 2-haloalkoxy-3-substituted quinolines via the cyclization of 2-alkynylanilines with TMSCF 3 and THF.