Jun 8, 2009 · JWH-018 is a synthetic cannabinoid that binds CB1 and CB2 receptors, with a moderate selectivity for the CB2 receptor and produces effects consistent with naturally occuring cannabinoids with THC. Dr. John W. Huffman first synthesized it, and it has be

Feb 22, 2010 · K2 contains two synthetic cannabinoids created at Clemson University. Chemistry professor John W. Huffman said an undergraduate student working in his lab actually created one of the compounds, called JWH-018 after Huffman's initials. Check around the middle of the article.

Dec 19, 2008 · A series of ADMET studies were completed to assess the toxicological profile of JWH-018. These studies were chosen to screen for several key issues and are typically used to identify major potential problems early in the development sequence of a new drug candidate. To fully evaluate the safety of JWH-018 more studies are needed.

Oct 8, 2010 · Secondly, X is looking for an appropriate ratio of JWH-018 to herbal substrate. In the name of harm reduction, X plans on creating a mixture that is well know, explained, and marked in contents and dosage, and has seen everything from 1g/200g to 1g/10g.

May 12, 2009 · SWIM ordered JWH-018 and was wondering if he could mix the JWH with his liquid nicotine, then vaporize it in his electronic cigarette. Does anyone know if the JWH would have an adverse reaction to the substances in the nicotine listed below? tobacco essencial oil tobacco lead oil nicotine (from tobacco leaf) 2,3,5-trimethylpyrazine

Sep 20, 2009 · Question was also asked recently on this forum in a thread titled "Routes of administration" where it was pointed out by a Swimmer that snorting would not be an efficient route of administration due to the nature of JWH-018. That reply also linked to the drug info article for JWH-018 which had this to say regarding the matter:

Feb 8, 2010 · Goal - dissolve JWH-018 into ethanol Items: 30 ml bottle with measured dropper 150mg of JWH-018 (supposed 99.5% pure, off white and granulated) 30ml ethanol (estimated 80% ethanol) coffee mug filled with hot water Steps: Pour ethanol into bottle Place 30ml bottle into hot water bath (coffee cup) Add 150mg of JWH-018 into ethanol Wait 10 minutes ...

Oct 5, 2009 · Jwh 018 and 073 are very similar to smoke. I have made smoking blends with each and found that gram for gram, a blend made with an equivalent dose of 073 (1 gram) per 1 oz. of substrate, 073 is weaker than 018. In the best smoking blend I has ever made, he used both of these substances in equal amounts, and the combination was better than ...

Nov 7, 2009 · JWH-018 - Probably lower than JWH-073 (not tested, but expected from structure) JWH-073 - <5mg/2.5ml JWH-250 - >10mg/ml (10mg/ml dissolved within 15 minutes under gentle heat, and didn't precipitate out when returned to room temperature) Vegetable Oil: JWH-073 - Insoluble Heptane (no, i wasn't planning on drinking it):

Mar 15, 2010 · Huffman says it's very easy to make JWH-018 with commercially available ingredients, and that a knowledgeable person should be able to read his research paper and figure it out. SWIM assumes it would take a chemist, but SWIM wonders if the home hobbyist would be able to make his own JWH-018.