L cells secrete glucagon-like peptide-1, an incretin, peptide YY 3-36, oxyntomodulin and glucagon-like peptide-2. L cells are primarily found in the ileum and large intestine (colon), but …

With a view to home in on what an L-cell is, we here present an overview of available data on L-cell development, L-cell peptide expression profiles, peptide production and secretory patterns …

Dec 1, 2006 · Early studies on L-cell secretagogues used antibodies that targeted a mid-sequence epitope of glucagon, resulting in detection of glicentin/oxyntomodulin (i.e., …

L cells are neuroendocrine cells producing glucagon-like peptide 1 (GLP1), glucagon-like peptide 2 (GLP2), peptide YY (PYY), glicentin (Fig. 1), and oxyntomodulin (Böttcher et al. 1984; Fiocca …

L-cells, which have traditionally been described as having a distinct cone-shaped morphology, secrete the products of cleavage by prohormone convertase 1; GLP-1, glucagon-like peptide 2 …

Goldspink et al. generate human ileal organoids with fluorescently-labeled GLP-1-secreting L-cells, which respond to nutritional stimuli and are used for transcriptomic, peptidomic, and …

Jun 1, 2021 · With a view to home in on what an L-cell is, we here present an overview of available data on L-cell development, L-cell peptide expression profiles, peptide production …

Glucagon-like peptide 1 (GLP-1) is a hormone released from enteroendocrine L cells. Although first described as a glucoregulatory incretin hormone, GLP-1 also suppresses inflammation …

Feb 13, 2019 · Enteroendocrine cells produce a range of gut hormones that have key roles in the coordination of food digestion and absorption, insulin secretion and appetite.

Dec 6, 2008 · By generating transgenic mice with L cell-specific expression of a fluorescent protein, we studied the characteristics of primary L cells by electrophysiology, fluorescence …