MAP kinase-activated protein kinase 2 is an enzyme that in humans is encoded by the MAPKAPK2 gene. [5][6][7] This gene encodes a member of the Ser/Thr protein kinase family. …

Mar 8, 2019 · Post-transcriptional regulation of genes harboring adenine/uridine-rich elements (AREs) in their 3′-untranslated region (3′-UTR) is controlled by MAPK-activated protein kinase …

Jan 18, 2006 · The two MAPK-interacting kinases, MNK1 and MNK2 5,6, which each contain only one catalytic domain, are also activated by both the ERK and p38 pathways. RSKs and MSKs …

Dec 25, 2024 · Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2, or MK2) is a kinase belonging to the MAPKAPK family, a group of kinases activated by MAPK …

our results suggest that the MAPKAPK2 plays a key role in Sophoridine-inhibited growth and invasion in colorectal cancers. Overexpression of microRNA-490-3p alleviates inflammation …

The immediate downstream serine/threonine kinase and substrate of p38 MAPK, mitogen-activated-protein-kinase-activated-protein-kinase-2 (MK2) protects cells against stressors by …

MAPKAPK2, also known as MK2, is a protein kinase that phosphorylates TTP at specific sites, leading to the formation of a complex with 14-3-3 proteins. This complex prevents the …

MSK1 and MSK2 (or RSKB), downstream targets of ERK1, ERK2, and p38 MAPK, play a versatile role in transcriptional and translational regulation, and affect inflammatory responses …

Aug 1, 2017 · MK2 is a serine-threonine kinase downstream to p38 and is activated directly through phosphorylation of p38 under stress and inflammatory stimulus. MK2 has been shown …

Jan 14, 2025 · Here, we identified p38 mitogen-activated protein kinases (p38 MAPK, a.k.a. p38) as a key player in promoting cell death and the inflammatory response to ischemic stress …