The term monoclonal gammopathy of renal significance (MGRS) was introduced by the International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …

Aug 13, 2019 · Renal biopsy is mandatory and demonstration of monoclonal immunoglobulin in kidney, along with the corresponding immunoglobulin in serum or urine, is key to establish the …

Dec 3, 2018 · Accordingly, in this Expert Consensus Document, the IKMG redefines MGRS as a clonal proliferative disorder that produces a nephrotoxic monoclonal immunoglobulin and does …

Monoclonal gammopathy of renal significance (MGRS) is a recognized clinical entity. Literature regarding treatment and its outcomes in MGRS is sparse due to the rarity and misdiagnosis of …

Monoclonal gammopathy of renal significance (MGRS) includes all kidney disorders caused by a monoclonal protein (M-protein) secreted by a small plasma cell clone or other B-cell clones in …

Nov 13, 2019 · Results: A total of 8 patients were treated at our center for MGRS between 3/2015 and 1/2019. The type of MGRS diagnosis was PGNMID in 5 patients, C3 glomerulopathy in 1 …

May 19, 2021 · Monoclonal gammopathy has emerged as an important cause of kidney injury and is responsible for a variety of glomerular, tubulointerstitial, and vascular lesions within the …

Monoclonal gammopathy of undetermined significance (MGUS) is a benign condition with malignant potential. Based on the associated paraprotein, MGUS can be separated into two …

Dec 30, 2022 · According to an IMKG consensus report, a renal biopsy is required for the diagnosis of MGRS, with light microscopy and immunofluorescence microscopy evaluations …

Nov 21, 2013 · Monoclonal gammopathy of renal significance (MGRS) is defined by the causal relationship between a small B-cell clone and renal disease, usually through deposition of the …