Jun 13, 2005 · Nedocromil is a anti-inflammatory agent and can be administered directly to the bronchial mucosa. It has significant inhibitory effect on allergen-induced early and late asthmatic reactions and on bronchial hyperresponsiveness.

Nedocromil. Nedocromil 2% (Alocril) is a pyranoquinoline derivative of cromolyn that inhibits various activities on multiple cells involved in allergic inflammation including eosinophils, neutrophils, macrophages, mast cells, monocytes and platelets.

Nedocromil sodium is a medication considered a mast cell stabilizer which acts to prevent wheezing, shortness of breath, and other breathing problems caused by asthma. It is administered by an inhaler under the brand name Tilade, and as …

Nedocromil inhibits activation and release of inflammatory mediators such as histamine, prostaglandin D2 and leukotrienes c4 from eosinophils. The mechanism of action of nedocromil may be due partly to inhibition of axon reflexes and release of sensory neuropeptides, such as substance P, neurokinin A, and calcitonin-gene related peptides.

Feb 1, 2025 · Nedocromil is used to help prevent symptoms of asthma or bronchospasm (wheezing or difficulty in breathing). When this medicine is used regularly, it decreases the number and severity of asthma attacks. Nedocromil will not relieve an asthma or bronchospasm attack that has already started.

Nedocromil is a pyranoquinoline derivative of cromolyn that inhibits various activities on multiple cells involved in allergic inflammation. It inhibits the activation and release of inflammatory mediators and has been shown to improve clinical symptoms in the control of ocular pruritus and irritation in the treatment of SAC.

Feb 10, 2020 · Inhibits the activation of and mediator release from a variety of inflammatory cell types associated with hypersensitivity reactions including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets; it inhibits the release of histamine, leukotrienes, and slow-reacting substance of anaphylaxis. Low (<4%)

Mar 28, 2024 · Generic name: Nedocromil (oral inhalation) [ ne-doe-KROE-mil-in-hil-AYE-shun ] Drug class: Mast cell stabilizers. Medically reviewed by Drugs.com. Last updated on Mar 28, 2024. Uses; Before taking; Warnings; Dosage; Side effects; Overdose; Uses of Nedocromil: It is used to treat asthma. Do not use nedocromil (oral inhalation) to treat an asthma ...

Nedocromil sodium: a review of the evidence for a dual mechanism of action. Nedocromil sodium: a review of the evidence for a dual mechanism of action. Nedocromil sodium: a review of the evidence for a dual mechanism of action Clin Exp Allergy. 2000 Apr;30(4):461-8. doi: 10.1046/j.1365-2222.2000.00769.x. ...

nedocromil sodium A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.