The PC12 cell line has been used to get more information about diseases of the brain. It has been used in research of hypoxia, where acute hypoxia induces exocytosis and prolonged hypoxia …

The PC12 cell line is one of the most commonly used in neuroscience research, including studies on neurotoxicity, neuroprotection, neurosecretion, neuroinflammation, and synaptogenesis. …

PC12 cells have been widely used as a model for neural differentiation and as such they have been used to examine the effects of differentiation on exocytotic release and specifically …

The PC12 cell line, a classical model in neurobiology, is a neural crest-derived cell line that exhibits features of neuronal differentiation in response to NGF (Hans et al., 2001). From: …

Apr 14, 2020 · This paper aims to characterise the use of two distinct variants of PC12 cells as well as describe their differentiation and neuronal outgrowth with diverse NGF concentrations …

The PC12 cell line is a classical neuronal cell model due to its ability to acquire the sympathetic neurons features when deal with nerve growth factor (NGF). In the present study, the authors …

Jan 4, 2023 · We depict the cellular source, culture condition, differentiation methods, transfection methods, drugs inducing AD, general approaches (evaluation methods and metrics), and in …

Pheochromocytoma PC 12 cell line is an established model system for neurosecretion and neuronal differentiation, particular to study cellular responses to nerve growth factors (NGF) …

PC12 cells that overexpress the human insulin receptor, termed PC12-INSR cells, were generated by transfecting cells with a mammalian expression vector that directs the synthesis …

May 31, 2002 · PC12 cells continue to be an important model system by which to study how hormones, neurotransmitters, and neurotrophins initiate multiple signaling pathways that …