AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-α (PPAR-α) are critical regulators of short-term and long-term fatty acid oxidation, respectively. We …

Comprehensive studies support the notion that the peroxisome proliferator-activated receptors, (PPARs), PPARalpha, PPARbeta/delta, and PPARgamma, regulate cell growth, …

amp-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-α (PPAR-α) are critical regulators of fatty acid oxidation. AMPK phosphorylates and inhibits acetyl CoA …

Since AMPK is an important regulator in energy metabolism, it may be a key downstream target of PPARs, as indicated by the convergence of PPAR agonists' actions on AMPK. Overall, the …

PPARα activators including fenofibrate and WY14643 activate AMPK signaling pathway in a receptor-independent manner (Figure 4). However, the mechanisms of these ligands on …

AMPK activation increases fatty acid oxidation in skeletal muscle by decreasing malonyl CoA concentrations. Activation of AMPK by 5-aminoimidazole-4-carboxamide ribonucleoside …

Jul 1, 2011 · Activation of adenosine monophosphate-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy through peroxisome proliferators-activated receptor-α …

Activation of adenosine monophosphate-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy through peroxisome proliferators-activated receptor-α (PPARα) …

Mar 20, 2016 · The combined activation of the cellular energy sensor AMP ‐activated protein kinase (AMPK) and the nuclear transcription factor peroxisome proliferator‐activated receptor …

Aug 1, 2011 · Schematic representation of cardioprotective signaling pathways elicited by PPAR-γ and AMPK against I/R injury. Activation of PPAR-γ by various ligands leads to the up …