Progressive supranuclear palsy is characterized by decreased cognition, abnormal eye movements (supranuclear vertical gaze palsy), postural instability and falls, as well as Parkinsonian features and speech disturbances 1-3.

Mar 5, 2024 · Midbrain to pons ratios as measured on midline sagittal images have been found useful in confirming midbrain atrophy in the setting of progressive supranuclear palsy (PSP). A measurement method was described by Oba et al. on the midsagittal MR image using free-hand regions of interest to define the ratio of areas (Figure 1) 1:

Brain MRI was repeated in 2022 and revealed moderate midbrain atrophy, which is considered to be a supportive feature for PSP diagnosis. The characteristic “hummingbird” sign was observed on sagittal T1 images (see Figure 1 B).

Gradual problems with speech, gait, eye movements and cognition. Sagittal midline image demonstrates atrophy of the midbrain which is concave at its cranial margin (hummingbird sign). This concavity is also evident laterally on axial images (morning glory sign).

Apr 24, 2013 · MRI-based measurements used to diagnose progressive supranuclear palsy (PSP) typically lack pathologic verification and are not easy to use routinely. We aimed to develop in histologically proven disease a simple measure of the midbrain and …

Jun 27, 2005 · Objective: To evaluate the area of the midbrain and pons on mid-sagittal MRI in patients with progressive supranuclear palsy (PSP), Parkinson disease (PD), and multiple-system atrophy of the Parkinson type (MSA-P), compare these appearances and values with those of normal control subjects, and establish diagnostic MRI criteria for the diagnosis ...

May 14, 2013 · Objectives: MRI-based measurements used to diagnose progressive supranuclear palsy (PSP) typi-cally lack pathologic verification and are not easy to use routinely. We aimed to develop in histolog-ically proven disease a simple measure of the midbrain and pons on sagittal MRI to identify PSP. (MSA) (n 7), and in controls (n 8).

MRI-based measurements used to diagnose progressive supranuclear palsy (PSP) typically lack pathologic verification and are not easy to use routinely. We aimed to develop in histologically proven disease a simple measure of the midbrain and pons on sagittal MRI to identify PSP.

This paper discusses using brain magnetic resonance imaging (MRI) to diagnose PSP, and a review of relevant literature addresses the diagnostic value of MRI in PSP. Keywords: hummingbird sign, magnetic resonance imaging, Parkinson plus syndrome, progressive supranuclear palsy

Sep 28, 2014 · Investigation of choice is MRI. Mid brain atrophy is must. Hummingbird sign also known as the penguin sign on mid sagittal sections as in our case. The key is a flattening or concave outline to the superior aspect of the midbrain which should be upwardly convex.