A polyamine is an organic compound having two or more amino groups. Alkyl polyamines occur naturally, but some are synthetic. Alkylpolyamines are colorless, hygroscopic, and water …

In vivo production of polyamine begins with the intake of amino acids (arginine, lysine, and methionine) through food, serving as substrates for polyamine synthesis through the action of …

Increased polyamine intake elevates blood spermine levels in humans, in spite the fact that many foods contain spermidine much more than spermine. Polyamine binds to the cell membrane, …

Jun 9, 2021 · Putrescine, spermine, and spermidine are the important polyamines (PAs), found in all living organisms. PAs are formed by the decarboxylation of amino acids, and they facilitate …

Dec 4, 2023 · This review examines a variety of topics, such as polyamine source and metabolism, including metabolism, transport, and the potential impact of polyamines on health …

The balance of polyamine synthesis and catabolism is critical to the regulation of cellular polyamine levels. Alterations in polyamine metabolism in vitro, in genetically engineered …

Sep 4, 2018 · This Review discusses new insights into molecular mechanisms that link the dysregulation of polyamine metabolism with carcinogenesis and strategies for targeting this …

The polyamine system has been identified in all organisms, and plays an important role in numerous essential cellular functions, including growth, division, and signalling cascades, as …

A polyamine is a cationic compound that has at least two primary amino groups (–NH) that bind to DNA. From: International Journal for Parasitology, 2014

Polyamine metabolism influences both tumor cells and the tumor microenvironment by modulating immune cell phenotypes—shifting them towards either tumor suppression or immune evasion …