A polyphosphate is a salt or ester of polymeric oxyanions formed from tetrahedral PO 4 structural units linked together by sharing oxygen atoms. Polyphosphates can adopt linear or a cyclic (also called, ring) structures.

Polyphosphate may have utility as a hemostatic agent, whereas antagonists of polyphosphate may function as novel antithrombotic/anti-inflammatory agents. The detailed molecular mechanisms by which polyphosphate modulates blood clotting reactions remain to be elucidated.

Polyphosphate (polyP) is an inorganic polymer that has recently been shown to be secreted by activated platelets. It is a potent modulator of the blood clotting and complement systems in hemostasis, thrombosis, and inflammation.

Polyphosphate (polyP) is a linear polymer of a few to many hundreds of phosphate (P i) residues linked by high-energy phosphoanhydride bonds . This ubiquitous polymer is found in bacteria, protists, and mammalian cells, and it was likely present prebiotically .

Dec 19, 2023 · Studies have illuminated a possible link between high polyphosphate intake and cardiovascular issues. Here's what some of the findings suggest: A 2012 study published in the Journal of Biological Chemistry found that polyphosphates can induce vascular calcification, a risk factor for heart disease, by promoting the differentiation of vascular ...

Polyphosphate (polyP), a polymer of orthophosphate (PO 4 3-) of varying lengths, has been identified in all kingdoms of life. It can serve as a source of chemical bond energy (phosphoanhydride bond) that may have been used by biological systems …

Polyphosphate (polyP) is a highly anionic inorganic polymer composed of phosphate monomers, connected by high-energy phosphoanhydride bonds [25]. PolyP of varying lengths is ubiquitously found in every prokaryotic and eukaryotic cell.

Jan 1, 2021 · Polyphosphate (PolyP), formerly referred to as volutin granules, is ubiquitous with a diverse range of functions. PolyP is present in substantial amounts in prokaryotes and has extensively been researched for various enzymes and …

Aug 2, 2024 · Polyphosphate (polyP) is an evolutionary ancient inorganic molecule widespread in biology, exerting a broad range of biological activities. The intracellular polymer serves as an energy storage pool and phosphate/calcium ion reservoir …

Polyphosphate (polyP) has a very simple structure, consisting of a linear polymer of inorganic phosphates linked together via high energy phosphoanhydride bonds . PolyP is ubiquitous in biology, being found in all kingdoms of life and possibly even predating life on this planet .