
RUNX1 - Wikipedia
Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) and it is a protein that is encoded by …
RUNX1 Gene - GeneCards | RUNX1 Protein | RUNX1 Antibody
Dec 25, 2024 · RUNX1 (RUNX Family Transcription Factor 1) is a Protein Coding gene. Diseases associated with RUNX1 include Platelet Disorder, Familial, With Associated Myeloid …
Role of RUNX1 in hematological malignancies
Apr 13, 2017 · RUNX1 is a member of the core-binding factor family of transcription factors and is indispensable for the establishment of definitive hematopoiesis in vertebrates. RUNX1 is one …
RUNX1 Familial Platelet Disorder with Associated Myeloid Malignancies
Mar 4, 2021 · RUNX1 -FPDMM is characterized by thrombocytopenia with normal platelet size; bleeding is often greater than expected due to qualitative platelet dysfunction. Myeloid …
RUNX1 Research Program
RUNX1-FPD (also known as RUNX1-FPDMM or FPD-AML) is a rare inherited disease caused by a mutation in the RUNX1 gene, resulting in lower blood platelet counts, platelet dysfunction, …
RUNX1 gene - MedlinePlus
The RUNX1 gene provides instructions for making a protein called runt-related transcription factor 1 (RUNX1). Like other transcription factors, the RUNX1 protein attaches (binds) to specific …
RUNX1 and cancer - PubMed
Runt-related transcription factor 1 (RUNX1) is frequently involved in the progression of acute leukemia. However, emerging and discoverable RUNX1 somatic mutations, RUNX1 …
RUNX1 RUNX family transcription factor 1 [ (human)]
Feb 8, 2025 · RUNX1 predicts poor prognosis and correlates with tumor progression in clear cell renal carcinoma. RUNX1 promotes proliferation and migration in non-small cell lung cancer …
Runx1 Structure and Function in Blood Cell Development
In this review we focus on the founding member of the family, RUNX1, and its role in the transcriptional control of blood cell development in mammals. We summarize data showing …
The RUNX1/RUNX1T1 network: translating insights into …
RUNX1/RUNX1T1 is the most common fusion gene found in acute myeloid leukemia. Seminal contributions by many different research groups have revealed a complex regulatory network …