Feb 7, 2020 · Here, we summarised new insights into the role of SGOC metabolism in the progression of neuroblastoma (NB) with highly activated SGOC metabolism.

May 5, 2023 · This review comprehensively analyzes the expression pattern and metabolic flux of the SGOC pathway in multiple cancer backgrounds at the system level and to describe the …

Jun 17, 2024 · Serine–glycine-one-carbon (SGOC) metabolism was screened out to be responsible for the aggressive malignant properties and poor prognosis in HNSCC patients. A …

Aug 1, 2019 · Here we report that neuroblastoma cells with MYCN amplification show increased transcriptional activation of the serine-glycine-one-carbon (SGOC) biosynthetic pathway and …

Oct 1, 2020 · This review will focus on the participation of serine and glycine in the mitochondrial one-carbon (SGOC) pathway during cancer progression, with an emphasis on the genetic and …

Nov 25, 2015 · The serine, glycine and one-carbon (SGOC) network is a complex, cyclic system that converts serine and glycine into metabolic outputs necessary for cells to accomplish a …

Nov 20, 2014 · Flux analysis of serine shows that gene expression patterns can predict flux. The serine, glycine, one-carbon (SGOC) metabolic network is implicated in cancer pathogenesis, …

A novel, robust 4-gene signature based on SGOC was developed to stratify HNSCC patients into high- and low-risk groups. The differences in the TME and response to therapies were …

Jun 17, 2024 · Serine-glycine-one-carbon (SGOC) metabolism was screened out to be responsible for the aggressive malignant properties and poor prognosis in HNSCC patients. A …

This review comprehensively analyzes the expression pattern and metabolic flux of the SGOC pathway in multiple cancer backgrounds at the system level and to describe the possible role …