Oct 6, 2024 · An acute ST-segment elevation myocardial infarction (STEMI) arises from the occlusion of 1 or more coronary arteries, causing transmural myocardial ischemia and subsequent myocardial injury or necrosis.

ST-Segment Elevation Myocardial Infarction (STEMI) is a life-threatening medical emergency characterized by complete coronary artery occlusion, leading to myocardial ischemia and subsequent necrosis.

The clinical diagnosis of myocardial infarction (MI) relies on symptoms, electrocardiographic findings, and biochemical markers (troponin, serum creatine kinase, creatine kinase‐MB). 1, 2 Acute ischaemic syndromes are now classified as unstable angina/non‐ST‐elevation MI (UA/NSTEMI) and acute ischaemic syndromes with ST‐elevation MI ...

Jan 31, 2025 · Myocardial infarction refers to the death of cardiac muscle due to prolonged ischemia. It is commonly known as a heart attack. Myocardial infarction can occur at any age. Around 10% of cases are seen in people under 40 years, and about 45% in those under 65 years. The prevalence increases with age.

From here on, we focus on the management of acute ST-elevation myocardial infarction (STEMI), that is, the management of patients presenting with ischaemic symptoms and persistent electrocardiographic evidence of ST-segment elevation.

Sep 20, 2015 · Myocardial infarction is defined as sudden ischemic death of myocardial tissue. In the clinical context, myocardial infarction is usually due to thrombotic occlusion of a coronary vessel caused by rupture of a vulnerable plaque.

The clinical diagnosis of myocardial infarction (MI) relies on symptoms, electrocardiographic findings, and biochemical markers (troponin, serum creatine kinase, creatine kinase-MB). 1,2 Acute ischaemic syndromes are now classified as unstable angina/non-ST-elevation MI (UA/NSTEMI) and acute ischaemic syndromes with ST-elevation MI (STEMI). 1,2 ...

Mar 14, 2017 · We here review the pathophysiology of acute myocardial infarction and reperfusion, notably the temporal and spatial evolution of ischaemic and reperfusion injury, the different modes of cell death, and the resulting coronary microvascular dysfunction.

Describe the histologic features of acute myocardial infarction and explain pathophysiology underlying the histologic changes from initial infarction through fibrosis and relate to the laboratory diagnosis of myocardial infarction.

Jan 1, 2018 · Clinical characteristics including electrocardiogram (ECG) with ST elevation in at least two contiguous leads, serve to recognize the presence of ST-elevation MI (STEMI). Elevated myocardial necrosis biomarker levels and imaging techniques have been developed to further characterize the full range of STEMI patient characteristics [1].