ScvO2 in anormal person is expected to be 2-3% less than SvO2 because it contains predominantly SVC blood from the upper body (ie. ScVO2 < SvO2) blood from the upper body has a higher oxygen extraction ratio (OER), and thus a lower SO2 than IVC blood

Jan 7, 2019 · pCO2 gap is a surrogate for cardiac output; pCO2 gap = PcvCO2 - PaCO2; pCO2 gap >6 mmHg suggests a persistent shock state that may be amenable to fluid resuscitation +/- intrope support; a “ScvO2-cvaCO2gap-guided protocol” has been proposed to guide the management of septic shock

Aug 31, 2021 · The veno-arterial difference in the partial pressure of carbon dioxide (Pv-aCO 2 gap) has been increasingly recognized as a reliable tool to evaluate tissue perfusion and as a marker of poor outcome during circulatory shock, and it should therefore be part of an integrated clinical evaluation.

The PCO2 gap can be a marker of the adequacy of the cardiac output status in severe sepsis. A high PCO2 gap value (>0.8 kPa) can identify situations in which increasing CO can be attempted with fluid resuscitation in severe sepsis. The PCO2 gap carries an important prognostic value in severe sepsis. 1. Introduction

Since normal or high central venous oxygen saturation (ScvO 2) values cannot discriminate if tissue perfusion is adequate, integrating other markers of tissue hypoxia, such as central venous-to-arterial carbon dioxide difference (P cva CO 2 gap) has been proposed.

Taking ScvO2 < 73% and CO2 gap >6 mmHg values together to predict an oxygen extraction >30%, the positive predictive value is 100%; negative predicted value is 72%. Microcirculatory parameters, capillary perfusion rate and red blood cell velocity, decreased significantly over time.

Jul 17, 2017 · Recently a few cases at Genius General Hospital have arisen where cvO2% was misleading. Specifically, the cvO2% was elevated despite cardiogenic or hemorrhagic shock. This post will attempt to explore why this might occur.

Background: The difference between arterial and central venous carbon dioxide partial pressure (PCO 2 gap), a marker of oxygen delivery (DO 2) and oxygen consumption (VO 2) adequacy, has been evaluated as a promising prognostic tool in intensive care unit (ICU) patients.

We aimed to describe changes in central venous oxygen saturation (ScvO2 ) and venous-to-arterial carbon dioxide gap (dCO2 ) during an experimental stroke volume (SV) index (SVI)-guided hemorrhage and fluid resuscitation model in pigs.

Based on similar research in the care of community sepsis, a "ScvO 2 -central venous-to-arterial CO 2 (CvaCO 2 ) gap-guided protocol could be used for septic shock management."