The SHP-77 (Shadyside Hospital, Pittsburgh, PA) cell line is a biochemically stable continuously cultured cell line which has retained important features of SCLC. This cell line is an unusual undifferentiated large cell variant of small cell lung carcinoma.

Stability and utility of the unique human small cell carcinoma line SHP-77. Human tumor lines for cancer research. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Secretion of atrial natriuretic …

SHP-77 express neural cell adhesion molecule (NCAM), NHK-1, CD56 and the cell surface leucocyte antigen Leu-7(HNK-1;CD57). Other neuroendocrine markers are L-dopa decarboxylase and dense core secretory granules.

SHP-77 可用做检测51Cr 和111In 释放对体外细胞及裸鼠体内毒性的 靶标，用于评估肺癌患者的细胞和血清的免疫反应水平。 该细胞可用于评估接受

Jun 1, 1985 · SHP-77 can serve as an in vitro target in 51 Cr and 111 In release cytotoxicity assays as well as in in vivo nude mouse assays for evaluating immune reactivity of cells and serum from lung cancer patients.

SHP-77 cell line is human small cell lung carcinoma (SCLC) epithelial cell line established in 1977. SHP-77 expresses neural cell adhesion molecule (NCAM), NHK-1, CD56, and the cell surface leucocyte antigen Leu-7(HNK- 1;CD57).

SHP-77 epithelial cells were derived from a non-encapsulated primary lung tumor in the apex of the left upper lobe of a 54-year-old Caucasian male in 1977. This cell line has unique characteristics, combining morphological features of the undifferentiated large cell variant of small cell lung cancer (SCLC) with typical biochemical properties of ...

The SHP-77 cell line finds valuable applications in various research contexts. It serves as an in vitro target for 51 Cr and 111 In release cytotoxicity assays, facilitating the study of cytotoxic immune responses.

Jan 5, 2022 · Cell information for SHP-77. Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

SHP-77 can serve as an in vitro target in 51Cr and 111In release cytotoxicity assays as well as in in vivo nude mouse assays for evaluating immune reactivity of cells and serum from lung cancer patients.