A symporter is an integral membrane protein that is involved in the transport of two (or more) different molecules across the cell membrane in the same direction. The symporter works in the plasma membrane and molecules are transported across the cell membrane at the same time, and is, therefore, a type of cotransporter .

Mar 29, 2020 · Furthermore, all channel proteins are the examples of uniports, and Na/glucose symporter is an example of a symport, while Na/H antiporter is an example of antiport. In brief, uniport, symport, and antiport are the three types of integral membrane proteins, which participate in moving molecules across the cell membrane.

Jan 30, 2025 · For instance, in the case of glucose and sodium, the symporter protein binds both molecules. Sodium moves down its concentration gradient, providing energy to transport glucose against its gradient. This mechanism is essential for nutrient absorption in the intestines. Types Of Symporters. Symporters are classified based on the molecules they ...

This symporter is crucial for maintaining ion balance and regulating cell volume in various tissues, including the kidney and the inner ear. Overall, symport is an active transport mechanism that involves the simultaneous movement of two different molecules or ions in the same direction.

Coupled transport of two different molecules or ions through a membrane in the same direction by a common carrier mechanism (symporter). Compare: antiport, uniport.

The sodium iodide symporter (NIS) as an imaging reporter for gene, viral, and cell-based therapies.

The symporter is a large complex protein that is dependent on proper protein folding, posttranslational modifications, protein trafficking, cellular polarity, and cellular organization for its function. The symporter transports an iodide ion into the cell through an active process using sodium ions as cotransport molecules.

Feb 10, 2011 · The Na + /I-symporter (NIS) is responsible for the accumulation of iodide by the thyroid gland. It is localized to the basolateral membrane of thyroid follicular cells and co-translocates 2 Na + ions and 1 I - ion per transport cycle (Fig. 3).

Na-K-2Cl symporter – This specific cotransporter regulates the cell volume by controlling the water and electrolyte content within the cell. [15] The Na-K-2Cl Cotransporter is vital in salt secretion in secretory epithelia cells along with renal salt reabsorption. [16] Two variations of the Na-K-2Cl symporter exist and are known as NKCC1 and ...

Jul 22, 2023 · One well-known example of a symport system is the glucose-Na+ symporter. This transporter allows cells to uptake glucose from the blood by coupling its transport with that of sodium ions, capitalizing on the sodium gradient maintained by the cell.