Jan 21, 2021 · We evaluated the quantity of viral DNA from the serotypes AAV9, AAV6, and a mosaic AAV1&2, expressing green fluorescent protein (GFP) under the neuron-specific …

Current studies suggest the following hypothesis for the role of synapsin: synapsins bind synaptic vesicles to components of the cytoskeleton which prevents them from migrating to the …

Jan 10, 2020 · In the present study, we designed a novel vector which improves transgene expression in the central nervous system of a Gba knock-out K-14-lnl/lnl mouse model (25) …

Synapsins are a family of peripheral proteins that bind to the SV membrane. They are encoded by three genes: SYN 1, 2, 3. Alternative splicing results in a/b protein variants for each synapsin …

Dec 24, 2014 · Given their ability to bind both the vesicular membrane and actin filaments in a phosphorylation-dependent manner, the classical role attributed to synapsins is the reversible …

We evaluated the quantity of viral DNA from the serotypes AAV9, AAV6, and a mosaic AAV1&2, expressing green fluorescent protein (GFP) under the neuron‐specific synapsin promoter …

Aug 17, 1998 · In order to disclose the fine structural details of these differences, synapsin and synaptophysin distribution was studied by immunocytochemistry on ligated bovine splenic …

May 1, 2010 · In this review, we summarise the current knowledge about how the various members of the synapsin family are involved in the modulation of the pre-synaptic physiology.

We evaluated the quantity of viral DNA from the serotypes AAV9, AAV6, and a mosaic AAV1&2, expressing green fluorescent protein (GFP) under the neuron-specific synapsin promoter …

An AAV9 vector with the synapsin promoter was also used to deliver the mouse Gba gene to P5 Gba(flox/flox), Nestin-Cre mice via intraperitoneal injection. The treatment resulted in extended …