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In vitro assays for effector T cell functions and activity of ...
In this chapter, we describe an optimized version of T cell suppression assay designed to test the capacity of immune co-stimulatory agents to enhance priming and activation of T cells in the presence of Tregs.
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Immuno-Oncology T Cell Assays - Charles River …
Assessing immune synapse formation can provide insights into priming by antigen presenting cells. iTreg and CD4 Th cell differentiation are T cell assays developed to observe activation and polarization of T cell subsets.
TME-Aligned Model: Immuno-Oncology 3D Tumor Cell …
The 3D TME-aligned model maintains native TME, respecting original patient cell populations and promotes naïve behaviour of tumor and immune cells. Tumor cell lysis enhanced by Immune Therapeutic Agents can be evaluated in patient …
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