Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. [11]

Paclitaxel is a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark.

Paclitaxel (Taxol) | C47H51NO14 | CID 441276 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Jan 1, 2022 · Taxol (paclitaxel), a complex diterpenoid is the most potent, and widely used chemotherapeutic drug for treating different types of cancers, such as breast, ovarian, lung cancers, in addition to Kaposi's sarcoma.

Apr 22, 2024 · Taxol is a complex molecule, highly branched one that contains a taxane nucleus, which gives it its unique chemical properties. The main structural feature of taxol is that it has a 17-membered tetracyclic skeleton, with a total of 11 stereocenters.

Paclitaxel (formerly called taxol), an important anticancer drug, inhibits cell replication by binding to and stabilizing microtubule polymers.

Taxol, organic compound with a complex multi-ring molecule that occurs in the bark of Pacific yew trees (Taxus brevifolia). It is active against certain cancers of the lung, ovary, breast, head, and neck, disrupting cell division and interfering with separation of the nuclear chromosomes.

An understanding of this interaction, and particularly of taxol’s conformation in the binding pocket on tubulin, would provide an insight into the pharmacophore of taxol and why some structural changes are beneficial while others are detrimental to taxol’s activity.

Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it …

Taxol = paclitaxel | C47H51NO14 | CID 89493063 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.