Dec 19, 2024 · Transsynaptic signaling through trans-Tango reveals synaptic connections in the zebrafish nervous system, providing a valuable in vivo tool to monitor and interrogate neural circuits over time.

Feb 22, 2023 · The Max Planck Zebrafish Brain (“mapzebrain”) atlas at https://mapzebrain.org is a multimodal digital atlas of the 6-day postfertilization (dpf) larval brain, integrating data portals for transgenic lines, histological stains, and expertly curated neuroanatomical regions, as well as a growing number (currently ca. 4300) of single-neuron ...

Sep 14, 2015 · Using this platform and immunohistochemical detection of phosphorylated extracellular signal–regulated kinase (ERK) as a readout of neural activity, we have developed a system to create and...

May 27, 2019 · Understanding brain-wide neuronal dynamics requires a detailed map of the underlying circuit architecture. We built an interactive cellular-resolution atlas of the zebrafish brain at 6 days post-fertilization (dpf) based on the reconstructions of over 2,000 individually GFP-labeled neurons.

The larval zebrafish optic tectum has emerged as a prominent model for understanding how neural circuits control visually guided behaviors. Further advances in this area will require tools to monitor and manipulate tectal neurons with cell type specificity.

Nov 22, 2024 · Here, we reconstruct and analyze a synaptic wiring diagram of the larval zebrafish brainstem to predict key functional properties and validate them through comparison with physiological data.

Jan 22, 2024 · These results provide a detailed map of cell types and brain areas in the zebrafish telencephalon, identify core components of neuromodulatory networks, highlight the cell-type specificity of neuropeptides and GPCRs, and begin to decipher the logic of combinatorial neuromodulation.

One of the most important advantages of zebrafish is its small brain size, both at larval and adult stages. Small brains enable exhaustive measurements of neuronal activity patterns by optical imaging and facilitate large-scale reconstructions of wiring diagrams by …

In the last 20 years, the zebrafish has proven to be an excellent model organism to study neurogenesis in the embryo. Recently, this vertebrate has also become a model for the investigation of adult neurogenesis and neural regeneration.

Zebrafish larvae can learn to adapt their motor actions to achieve a variety of goals, such as reducing energy expenditure when their actions are futile. Two groups have recently investigated the neural correlates of this experience-dependent behavior - …