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2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting.
The EVAR II trial: Endovascular approach when unfit for open …
Jun 23, 2013 · Image: PD 1. The EVAR II trial compared endovascular abdominal aortic aneurysm repair with no intervention in patients unsuitable for the open procedure. 2. There were significantly fewer aneurysm-related deaths in the endovascular group, compared to no intervention. 3. The rates of complication and reintervention were similar to the rates observed in EVAR I. Original
Landmark Trials & Summaries: The Classics in Medicine - 2 Minute …
Title Year Journal Citations Key findings; The UKPDS: Reducing the risk of diabetes-related morbidity and mortality: 1998: Lancet: 20,000: 1. For patients with type 2 diabetes mellitus, pharmacologic blood glucose control with sulfonylureas or insulin significantly reduces the risk of microvascular complications, but not macrovascular complications
Ticagrelor monotherapy reduces bleeding risk compared to dual ...
Sep 25, 2024 · 1. Ticagrelor was non-inferior to DAPT for the incidence of major adverse cardiovascular and cerebrovascular events. 2. Ticagrelor monotherapy significantly reduced the likelihood of BARC 3 or 5 bleeding. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with acute coronary syndrome (ACS) receive dual antiplatelet therapy (DAPT) for 12 months post-stenting to reduce the risk
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2 Minute Medicine® was created in 2012 by Marc D. Succi, MD, a physician at Harvard Medical School and Massachusetts General Hospital, to fill the need for professional curation and accurate reporting of the medical literature milieu.
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2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting.
Semaglutide reduces heart failure events in patients with …
Sep 24, 2024 · 1. Patients in the semaglutide group reported fewer heart failure events than those in the placebo group. 2. No significant difference was observed between groups for cardiovascular death alone. Evidence Rating Level: 1 (Excellent) Study Rundown: Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure, affecting patients with obesity,
Balanced intravenous solutions reduce risk of hyperchloremia in …
Jan 5, 2023 · 1. In a randomized controlled trial of critically ill pediatric patients requiring intravenous fluid therapy, children receiving saline were significantly more likely to have a serum chloride rise of 5 mEq/L than those receiving either gluconate/acetate-buffered solution or lactate-buffered solution. 2. The odds of a serum chloride rise within 48 hours were reduced by 50%
Semaglutide improves cardiovascular outcomes in obese patients …
Jan 5, 2024 · In-Depth [randomized controlled trial]: The current study was a multi-center, double-blind, randomized, placebo-controlled trial to demonstrate the superiority of semaglutide compared to placebo in treating obese patients without diabetes at cardiovascular risk. Patients aged 45 years or older who had a body mass index of 27 or greater and had established cardiovascular disease were eligible ...