Neurosense finalizing protocol for Phase 3 ALS trial of PrimeC
Dec 19, 2024 · In PARADIGM (NCT05357950), a completed Phase 2b study, PrimeC was tested against a placebo, both taken as two tablets by mouth twice daily for six months, in 68 adults …
Top 10 ALS news stories of 2024
Dec 30, 2024 · Read this story here. No. 8 – COYA 302 immune-modulating therapy shows promise in small early trial. Coya Therapeutics’ investigational therapy COYA 302 was found …
Largest ALS patient-based stem cell, biodata resource now open
Nov 21, 2024 · The largest of its kind, the repository contains biological and clinical data from nearly 1,000 ALS patients, as well as specialized nerve cells called induced pluripotent stem …
FDA outlines steps to consider accelerated approval of CNM-Au8
Dec 11, 2024 · The therapy’s developer, Clene, said it will put together an application in the coming months, with the goal of submitting it in mid-2025. “We are incredibly grateful for the …
ALS respiratory data now available to researchers worldwide
Oct 29, 2024 · Developed under a collaboration between the nonprofit Target ALS and Zephyrx, the database features respiratory function data collected remotely and over time using …
Auttx gets ALS Network grant to develop new treatments for ALS
Nov 5, 2024 · Faster route to treatments for ALS. In ALS, certain proteins tend to form toxic clumps inside neurons and contribute to cell damage. A hallmark protein that’s dysfunctional in …
Brain scans may predict ALS risk in C9ORF72 mutation carriers
Nov 29, 2024 · The findings suggest that looking for changes in brain structures could help predict which people with C9ORF72 mutations will develop ALS.. The study, “ Longitudinal Magnetic …
Approval request starting in Canada for PrimeC in treating ALS
Oct 14, 2024 · Top-line data from the main trial showed that PrimeC treatment for six months tended to slow disease progression, as assessed by the ALS Functional Rating Scale-Revised …
Tiziana wins funding for small clinical trial in ALS of intranasal ...
Nov 22, 2024 · The upcoming trial intends to investigate the safety and effectiveness of two foralumab doses in 20 ALS patients. It builds on positive findings from multiple sclerosis (MS) …
Feeding tube best placed before major weight loss with ALS: Study
Dec 24, 2024 · People with amyotrophic lateral sclerosis (ALS) who get a feeding tube placed after losing a lot of weight are more likely to die within a few months than those who receive …