Unit 2, Section 4: DL/I Function Codes

SOLVED:Two protein kinases, K 1 and K 2, function sequentially in an intracellular signaling pathway. If either kinase contains a mutation that permanently inactivates its function, no response is seen in cells when an extracellular signal is received. A different mutation in K 1 makes it permanently active, so that in cells containing that mutation a response is observed even in the absence of an extracellular signal. You characterize a double-mutant cell that contains K 2 with the inactivating

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